Advice & Analysis
Sequencing, Bioinformatic or Omic Experimental Design Advice
We offer expert advice on all aspects of sequencing and bioinformatics. Initial consultations are free of cost. For an informal chat, please contact: enquiries@gbiocore.co.uk
Grant Bid Advice & Support
We can support your bid at any stage.
Preliminary data analysis, including public datasets.
Power calculations.
Methods text.
Advice on experimental design.
As named Co-investigators if useful.
Sequencing Protocol Advice
We keep up-to-date with current advances omic technologies and library preparation methods.
Having expertise in analysis we can also advise on what protocol to use when.
How many samples, reads, cells, groups will get you the most out of your budget?
For example, when should you use Parse, 10x or Illumina for single cell.
For example, when should you use GeoMx, CosMx, Xenium or Visium HD for spatial omics.
Bioinformatic Analysis Advice
Stuck with code?
Not sure what method is best.
We are always happy to chat and advise where possible.
Not getting results you expect. Does your data need corrected?
Feel free to show us your results and we are happy to chat informally.
Analysis Service
We offer an expert, comprehensive bioinformatic analysis service, at competitive rates. For more information or an informal chat, please contact: enquiries@gbiocore.co.uk
Bulk RNA-seq, Proteomics or Metabolomics
Standard price = £750
From raw data to detailed, manuscript ready analysis with reports, and expert discussion on findings.
Unlimited differential comparisons and correction if needed.
All R code and methods supplied.
Includes but not limited to: PCA; Volcano; MA; Heatmaps; Boxplots; Pathway Analysis; Upstream Regulator Analysis; Overlap (Venn-Like); Fold-vs-Fold; Signatures & Biomarkers; Pathway Networks.
Single Cell RNA-seq
Standard price = £2,500
With an antibody derived tag layer (CITE-seq) = £3,000
From raw data to detailed, manuscript ready analysis, and expert discussion on findings.
All R code and methods supplied.
Includes but not limited to: QC; Filtering; Doublet Removal; Dimensionality Reduction (PCA); Integration; UMAP; Clustering and Cluster Biomarkers; Cell Type Identification; Cleanup; Subsets; Differential Comparisons; Ligand - Receptor Interactions; Trajectory Analysis
Spatial Methods - Visium, Xenium or CosMx
Standard price = £3,500
With matched single cell = £5,000
From raw data to detailed, manuscript ready analysis, and expert discussion on findings.
All R code and methods supplied.
Includes but not limited to: Re-segmentation; TMA separating; QC; Filtering; Dimensionality Reduction (PCA); Integration; UMAP; Clustering and Cluster Biomarkers; Cell Type Identification; Cleanup; Subsets; Differential Comparisons; Ligand - Receptor Interactions; Trajectory Analysis; Niche Analysis; Structure Identification.
GeoMx
Standard price = £1500
From raw data to detailed, manuscript ready analysis with reports, and expert discussion on findings.
Unlimited differential comparisons, replicate merging and correction.
All R code and methods supplied.
Includes but not limited to: PCA; Volcano; MA; Heatmaps; Boxplots; Pathway Analysis; Upstream Regulator Analysis; Overlap (Venn-Like); Fold-vs-Fold; Signatures & Biomarkers; Pathway Networks.